The effect of Nigella sativa (NS), Date palm pollen (DPP), vitamin D and omega 3 as dietary supplements on blood biochemical markers in mice

Mahdie Hemati ©, Ali mohammad Abdoli , Majid Naghibzadeh, Hamide Hemati

The effect of Nigella sativa (NS), Date palm pollen (DPP), vitamin D and omega 3 as dietary supplements on blood biochemical markers in mice

کد: G-42517

نویسندگان: Mahdie Hemati ©, Ali mohammad Abdoli , Majid Naghibzadeh, Hamide Hemati

زمان بندی: زمان بندی نشده!

برچسب: بیوشیمی

دانلود: دانلود پوستر

خلاصه مقاله:

Background and Aim

Infertility is one of the major problems among young couples can occur for a variety of reasons. Numerous findings showed that reactive oxygen species (ROS) can strongly affect various sperm parameters. Research showed that the use of antioxidants such as Nigella sativa (NS), Date palm pollen (DPP), vitamin D and omega 3 can be effective in reducing the damage caused by free radicals. The aim of this study was to investigate the effects of mentioned supplements on blood biochemical, inflammatory factor and sex hormone levels in male mice.

Methods

Animals were divided to 2 groups (6 rats in each group) as follows: control group that received saline solution /kg and group 2 that administrated combination of NS (200mg/Kg), DPP (200mg/Kg), and vitamin D (1.5 IU /g) and omega-3 (300mg/Kg). All solutions were administrated during 7 weeks via a gavage tube. Blood samples are taken from the hearts of rats to measure laboratory markers, mineral element, sex hormone and inflammatory factor of C-reactive protein (CRP) using an ELISA kit.

Results

The comparative plasma biochemical parameters (Triglyceride, Cholesterol, HDL, LDL, Urea, Creatinine, Total Protein, AST, ALT, LDH and CRP), minerals (Calcium, Phosphorus, Sodium and Potassium) and sexual hormone (Testosterone) were shown no significant different between control and experimental group except in FBS level that significantly reduced in treatment group and p value amount was less than 0.05.

Conclusion

The results showed that the combination therapy oh herbal medicine and vitamin has no side effects on body organs and blood markers

Keywords

Supplements; Laboratory markers; Oxidative stress.

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