Investigation the effect of COVID-19 on Mycobacterium tuberculosis challenges and opportunities (Systematic review)
نویسندگان: Mahya Najjari, Saman Soleimanpour ©
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Background and Aim
Coronavirus disease 19 (COVID-19) is a global threat that caused enormous damage. Mycobacterium tuberculosis (TB) is also one of the world’s top ten causes of death. SARS-CoV-2 and M. tuberculosis diseases have vital parallels with respect to cell entry, resistant reaction, and safe avoidance. So the aim of this study is to investigate the effect of COVID-19 on Mycobacterium tuberculosis challenges and opportunities.
This review article was performed within articles published at PubMed, Science Direct, Google Scholar, SID, and Cochrane until December 2021. The keywords were SARS-CoV-2, Mycobacterium tuberculosis, Confection. By searching this database; 84 articles were found, 51 of them by Reading titles and abstracts were removed. 33 articles were selected under the inclusion criteria. All articles were chosen from English and Persian articles.
Finally, 33 articles were included in the study. Co-infections of SARS-CoV-2 with M. tuberculosis were likely to result within the generation of cytokines like TNFα and IL-6 that led to exacerbated pathogenicity. Patients with latent/active TB were at a more noteworthy hazard for severe COVID-19 and those analyzed with SARS-Cov-2, ought to be taken up for the improvement of TB. COVID-19 could be related with tuberculosis reactivation in patients with different predispositions, such as diabetes mellitus, failure renal, and steroid utilization. Mask wearing and the avoidance of unnecessary physical contact helped to avoid releasing infected droplets for both COVID-19 and TB.
TB-endemic districts may have exacerbated pathologies within the setting of SARS-CoV-2 diseases; something that the scientific community will ought to pay attention to. However, need to be more research done at this topic.
Mycobacterium tuberculosis; SARS-CoV-2; COVID-19; co-infection
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