Antibiotic Resistance of Acinetobacter Species Isolated from Patients in Different Wards of Rouhani Hospital in Babol

Zahra Ahmadnia ©, Hossein Ghorbani, Samaneh Rouhi

Antibiotic Resistance of Acinetobacter Species Isolated from Patients in Different Wards of Rouhani Hospital in Babol

کد: G-63519

نویسندگان: Zahra Ahmadnia ©, Hossein Ghorbani, Samaneh Rouhi

زمان بندی: زمان بندی نشده!

برچسب: میکروب شناسی

دانلود: دانلود پوستر

خلاصه مقاله:

Background and Aim

The study of antibiotic resistance in bacteria is very important in the management of treatment and control of infectious diseases. The aim of this study was to determine the level of bacterial contamination and antibiotic resistance of Acinetobacter species isolated from patient samples in different wards of Rouhani اospital in Babol.

Methods

The information of patients from the hospital information system of Rouhani hospital in Babol in the first 6 months of 2021 was analyzed. Acinetobacter was detected by microbiological laboratory methods and microbial susceptibility testing was performed by disk diffusion method according to the standard of the Clinical and Laboratory Standards Institute (CLSI). For data analysis, SPSS software version 21 and frequency table were performed (P-value less than 0.05).

Results

Fifthly tow species of Acinetobacter were isolated from patients. Antibiotic resistance was as follows; Piperacillin / Tazobactam for 52 isolates (breakpoint: 18-20, resistant: 94.2%, intermediate: 0, sensitive: 5.8%: Confidence interval (CI): 83-98.5). Ceftazidime for 31 isolates (breakpoint: 15-17, resistant: 96.8%, intermediate: 3.2, sensitive: 0: CI: 81.5-99.8). Ceftriaxone for 40 isolates (breakpoint: 14-20, resistant: 100%, intermediate: 0, sensitive: 0: CI: 89.1-100). Meropenem for 52 isolates (breakpoint: 15-17, resistant: 100%, intermediate: 0, sensitive: 0: CI: 91.4-100). Amikacin for 51 isolates (breakpoint: 15-16, resistance: 88.2%, intermediate: 0, sensitive: 11.8: CI: 75.4-95.1). Gentamicin for 1 isolate (breakpoint: 13-14, resistant: 0, intermediate: 0, sensitive: 100: CI: 0.0-94.5). Ciprofloxacin for 52 isolates (breakpoint: 22-25, resistant: 92.3, intermediate: 3.8, sensitive: 3.8: confidence: 80.6-97.5). Trimethoprim / sulfamethoxazole for 1 isolate (breakpoint: 11-15, resistant: 0, intermediate: 0, sensitive: 100: CI: 0.0- 94.5).

Conclusion

High antibiotic resistance was observed in Acinobacter isolated from the samples. The importance of conducting antibiotic susceptibility testing prior to drug administration is effective in the treatment and control of drug resistance.

Keywords

Infection rate; Antibiotic resistance; Acinetobacter

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