Cutaneous manifestations of the Coronavirus Disease 2019 (COVID‐19):A systematic review and meta-analysis

Nooshin Nazarinejad, Negin Noorisepehr, Nazila Bostanshirin, Fatemeh Sameni ©

Cutaneous manifestations of the Coronavirus Disease 2019 (COVID‐19):A systematic review and meta-analysis

کد: G-06127

نویسندگان: Nooshin Nazarinejad, Negin Noorisepehr, Nazila Bostanshirin, Fatemeh Sameni ©

زمان بندی: زمان بندی نشده!

برچسب: میکروب شناسی

دانلود: دانلود پوستر

خلاصه مقاله:

Background and Aim

Since the onset of the 2019-nCoV disease (COVID-19), many skin manifestations have been reported in COVID-19 patients. This study aims to provide a systematic review and meta-analysis of various skin manifestations among patients with COVID-19 through case reports/case series and prevalence studies.

Methods

A systematic literature search strategy was conducted by reviewing original research articles published in Medline, Web of Science, and Embase databases in 2020. Statistical analysis was performed using STATA software, version 14.0 (Stata Corporation, College Station, Texas, USA) to report the global prevalence of skin manifestations among patients with COVID-19.

Results

Forty-three studies (35 articles were case reports/case series, and 8 articles were prevalence studies) were included in our study. A meta-analysis of prevalence studies showed that skin manifestations among patients with COVID-19 were reported in four countries (China, Thailand, France, and Italy), with an overall prevalence of 1.0% [(95% CI) 0.1–1.9] among 2,621 patients. Evaluation of the results of the case reports/case series revealed that, out of 54 patients with COVID-19, 48 patients (88.8%) showed skin manifestations. Erythematous rash (59.1%) and urticaria (14.8%) were the most common skin manifestation reported in studied patients.

Conclusion

Infection with 2019-nCoV may lead to skin manifestations with various clinical symptoms. These clinical features combined with clinical symptoms of COVID-19 may aid in the timely diagnosis of patients with COVID-19.

Keywords

coronavirus; 2019-nCoV; COVID-19; skin manifestations; meta-analysis

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